Effects of a Physical Activity Program in Psychobiological Profile of Individuals with Schizophrenia
Abstract
The purposes of the present study were to verify the therapeutic effects of a Physical Activity Program (PAP) in individuals with schizophrenia from public mental health care services of São Paulo; compare levels of depression, trait and state anxiety, mood and levels of pro-inflammatory components of the immune system (Interleukin-6, IL-6) and Tumor Necrosis Factor -alpha (TNF-alpha)). A PAP was performed for 12 weeks, twice a week, ~45 minutes each session and aerobic emphasis. 32 individuals diagnosed with schizophrenia (15 females and 17 males) were divided into Control Group (CG, n=11, did not participate in the PAP); Intermediate Group (IG, n=10, performed less than 70% of sessions) and Exercise Group (EG, n=11, performed more than 70% of sessions). Anamnesis, anthropometry, and the following assessments were applied before and after the PAP: Beck Depression Index (BDI), State-Trait Anxiety Inventory (STAI), Brunels Mood Scale (BRUMS), and levels of salivary IL-6 and TNF-alpha. After the PAP, there were no significant anthropometric changes in any of the groups. There was a statistically significant reduction (p<0.05) within the EG for the variables BDI (p=0.008), STAI-Trait (p=0.040), sub variable “depression” of the BRUMS (p=0.036), and IL-6 (p=0.028) level. It is concluded that the implementation of a simple PAP was able to promote favorable therapeutic effects in the participants, regardless of anthropometric changes.
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